American Cruise Line

American Cruise Line Cruise Deals

American Cruise Line cruise deals open the door to explore American's beautiful and iconic Rivers. American Cruise Line offers cruises on the Mississippi River, the Hudson River and the Columbia and Snake Rivers. Immerse yourself in the southern history and culture of the Mississippi from St. Paul to New Orleans. The stunning views and historical sites of the Hudson River are highlighted on a Hudson River Cruise. The Columbia & Snake river lets you explore the Pacific Northwest. Book now and get the best deals on your next American Cruise Line cruise vacation.

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Featured American Cruise Line Deals

Best American Cruise Line Deals by Destination

6 Day Columbia & Snake Rivers

ship American Pride itinerary Roundtrip Portland/Oregon dates Mar 22, 2027 - Oct 31, 2028

Fr $4,084

8 Day Columbia & Snake Rivers

ship American Pride itinerary Clarkston to Portland/Oregon dates Oct 18, 2026 - Jul 25, 2027

Fr $5,005

8 Day Columbia & Snake Rivers

ship American Pride itinerary Portland/Oregon to Clarkston dates Oct 11, 2026 - Jul 18, 2027

Fr $5,500

8 Day Columbia & Snake Rivers

ship American Song itinerary Portland/Oregon to Clarkston dates Sep 1, 2026 - Jun 22, 2027

Fr $6,153

8 Day Columbia & Snake Rivers

ship American Song itinerary Clarkston to Portland/Oregon dates Jul 27, 2027 - Apr 18, 2028

Fr $6,336

14 Day Columbia & Snake Rivers

ship American Song itinerary Jackson to Portland/Oregon dates Jun 23 - Aug 18, 2027

Fr $13,920

15 Day Columbia & Snake Rivers

ship American Song itinerary Portland/Oregon to Jackson dates Jul 20 - Aug 17, 2027

Fr $13,920

7 Day Hudson River Cruise

ship American Legend itinerary Albany to New York City dates Oct 22, 2026 - Oct 19, 2029

Fr $8,312

8 Day Hudson River Cruise

ship American Eagle itinerary New York City to Albany dates Sep 21, 2026 - Sep 20, 2027

Fr $6,287

8 Day Hudson River Cruise

ship American Eagle itinerary Albany to New York City dates Jun 21, 2027 - Jun 19, 2028

Fr $6,287

8 Day Hudson River Cruise

ship American Glory itinerary Albany to New York City dates Oct 11, 2026 - Oct 30, 2028

Fr $7,119

8 Day Hudson River Cruise

ship American Glory itinerary New York City to Albany dates Sep 25, 2027 - Oct 22, 2029

Fr $7,119

8 Day Hudson River Cruise

ship American Legend itinerary New York City to Boston dates May 29, 2027 - Jun 22, 2029

Fr $7,341

8 Day Hudson River Cruise

ship American Legend itinerary New York City to Albany dates Oct 1, 2026 - Oct 12, 2029

Fr $8,237

7 Day Mississippi River Cruise

ship American Heritage itinerary Roundtrip New Orleans dates Nov 19, 2026 - Apr 27, 2027

Fr $3,198

8 Day Mississippi River Cruise

ship American Splendor itinerary Chattanooga to Nashville dates Aug 3, 2027 - Oct 10, 2028

Fr $4,253

8 Day Mississippi River Cruise

ship American Splendor itinerary Memphis to New Orleans dates Mar 28, 2028 - Feb 28, 2029

Fr $4,253

8 Day Mississippi River Cruise

ship American Splendor itinerary Nashville to Chattanooga dates Jul 27, 2027 - Oct 3, 2028

Fr $4,253

8 Day Mississippi River Cruise

ship American Heritage itinerary Pittsburgh to Louisville dates Jul 10 - Aug 7, 2026

Fr $4,693

8 Day Mississippi River Cruise

ship American Heritage itinerary Louisville to Pittsburgh dates Jul 17 & 31, 2026

Fr $5,010

8 Day Mississippi River Cruise

ship American Serenade itinerary Tulsa to Memphis dates May 28, 2027 - May 19, 2029

Fr $5,223

8 Day Mississippi River Cruise

ship American Melody itinerary Saint Louis to Saint Paul dates Jul 30, 2027 - Jul 6, 2029

Fr $5,579

8 Day Mississippi River Cruise

ship American Melody itinerary Saint Paul to Saint Louis dates Aug 6, 2027 - Jul 13, 2029

Fr $5,579

10 Day Mississippi River Cruise

ship American Heritage itinerary Knoxville to Huntsville dates Jul 13, 2027 - Jul 12, 2028

Fr $6,554

15 Day Mississippi River Cruise

ship American Heritage itinerary New Orleans to Huntsville dates Jun 26, 2027 & Jun 25, 2028

Fr $7,995

15 Day Mississippi River Cruise

ship American Splendor itinerary Nashville to New Orleans dates Sep 21, 2027 & Oct 17, 2028

Fr $8,584

7 Day New England Cruise

ship American Navigator itinerary Boston to New York City dates Sep 17, 2027 - Oct 20, 2029

Fr $7,757

8 Day New England Cruise

ship American Glory itinerary Boston to New York City dates Sep 27, 2026 - Jun 4, 2028

Fr $6,287

Fr $7,119

8 Day New England Cruise

ship American Navigator itinerary Roundtrip Boston dates Jul 30, 2027 - Apr 28, 2029

Fr $7,341

8 Day New England Cruise

ship American Glory itinerary Roundtrip Boston dates Sep 20, 2026

Fr $8,732

14 Day New England Cruise

ship American Navigator itinerary Roundtrip Boston dates May 5 - Oct 6, 2028

Fr $13,801

8 Day Southeastern US

ship American Glory itinerary Amelia Island to Charleston/South Carolina dates Nov 17, 2026 - Apr 14, 2027

Fr $5,436

8 Day Southeastern US

ship American Glory itinerary Charleston/South Carolina to Amelia Island dates Nov 24, 2026 - Feb 4, 2028

Fr $5,436

8 Day Southeastern US

ship American Eagle itinerary Charleston/South Carolina to Amelia Island dates Nov 14, 2026 - Mar 10, 2028

Fr $5,931

8 Day Southeastern US

ship American Eagle itinerary Amelia Island to Charleston/South Carolina dates Apr 30, 2027 - Nov 13, 2028

Fr $5,931

8 Day Southeastern US

ship American Legend itinerary Amelia Island to Charleston/South Carolina dates Nov 28, 2026 - Dec 20, 2027

Fr $6,431

8 Day Southeastern US

ship American Legend itinerary Charleston/South Carolina to Amelia Island dates Nov 21, 2026 - Dec 27, 2027

Fr $6,431

14 Day Southeastern US

ship American Pioneer itinerary Saint Petersburg to Jacksonville dates May 7, 2027

Fr $13,019

15 Day Southeastern US

ship American Glory itinerary Amelia Island to Washington, D.C. dates Apr 28, 2027 & Apr 21, 2028

Fr $10,480

15 Day Southeastern US

ship American Eagle itinerary Amelia Island to Washington, D.C. dates May 21, 2027 & May 20, 2028

Fr $10,480

15 Day Southeastern US

ship American Legend itinerary Amelia Island to Washington, D.C. dates Mar 24, 2027 - Mar 21, 2029

Fr $11,455

8 Day Alaska-Inside Passage

ship American Constellation itinerary Roundtrip Juneau dates Jun 8, 2027 - Jul 24, 2028

Fr $6,658

11 Day Alaska-Inside Passage

ship American Constitution itinerary Roundtrip Juneau dates Aug 26, 2026

Fr $8,440

11 Day Alaska-Tours & Cruises

ship American Constitution itinerary Juneau to Ketchikan dates Jun 22, 2028 - Aug 8, 2029

Fr $9,183

11 Day Alaska-Tours & Cruises

ship American Constitution itinerary Ketchikan to Juneau dates Jul 2, 2028 - Aug 18, 2029

Fr $9,183

11 Day Alaska-N./S. Bound

ship American Constellation itinerary Juneau to Ketchikan dates Jul 27, 2027 - Aug 13, 2029

Fr $9,183

11 Day Alaska-N./S. Bound

ship American Constellation itinerary Ketchikan to Juneau dates Aug 6, 2027 - Aug 23, 2029

Fr $9,183

15 Day Alaska-N./S. Bound

ship American Constellation itinerary Juneau to Tacoma dates Sep 14, 2026 - Sep 9, 2029

Fr $9,603

15 Day Alaska-N./S. Bound

ship American Constellation itinerary Tacoma to Juneau dates May 25, 2027 - May 15, 2029

Fr $10,098

15 Day Alaska-N./S. Bound

ship American Constellation itinerary Fairbanks to Juneau dates Jul 6, 2027 - Jul 17, 2028

Fr $14,281

18 Day Alaska-N./S. Bound

ship American Constellation itinerary Fairbanks to Juneau dates Jul 21 & 31, 2026

Fr $16,806

18 Day Alaska-Tours & Cruises

ship American Ranger itinerary Fairbanks to Ketchikan dates Jun 2, 2027 - Aug 10, 2028

Fr $19,404

8 Day Puget Sound

ship American Constellation itinerary Roundtrip Tacoma dates Sep 28, 2026 - May 11, 2027

Fr $4,876

8 Day Puget Sound

ship American Constitution itinerary Roundtrip Tacoma dates Sep 19, 2026 - May 2, 2027

Fr $4,876

8 Day Puget Sound

ship American Spirit itinerary Roundtrip Tacoma dates Aug 7, 2026 - Jul 2, 2027

Fr $5,812

8 Day Puget Sound

ship American Ranger itinerary Roundtrip Tacoma dates Apr 22, 2027 - Apr 9, 2028

Fr $6,926

8 Day Puget Sound

ship American Pioneer itinerary Roundtrip Tacoma dates Mar 24 - Aug 4, 2028

Fr $6,926

All offers are based on select sailings and categories and are subject to availability at time of booking. All rates are per person based on double occupancy.

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