A South America cruise vacation offers a world of exploration that is as spectacular as it is diverse. As you sail past the dramatic coastline you are greeted with exotic ports of call, modern and energetic cities, diverse cultures and abundant wildlife. Settled by historic explorers, cities like Rio de Janeiro, Buenos Aires, Lima and Santiago showcase the rich history of South America and its many European roots and cultures. On a South America Cruise you can explore these colorful, modern and exciting South American ports, see their historic sights, sample local cuisines and learn about their varied cultures.
South America boasts some of the worlds most famous and breathtaking destination including Peru's mystical Machu Picchu's ancient ruins, Chile's spectacular fjords, Brazil's Iguazu Falls, the stunning Andes Mountains and even the astonishing Antarctica. Only on a cruise to South America can you take in all of these awe inspiring destinations for a memory that will last a lifetime.
The unique wildlife of South America is abundant. Listen to the chatter of monkeys in the Amazon, watch the seals basking on South America's beaches and see some of the world's most majestic penguins, whales and other wildlife. In the Amazon, cruise through the spectacular rainforests, float past native villages, learn about the history and cultures of the many indigenous tribes and discover the many species that make the Amazon ecosystem so incredible.
Over 180 South America cruise itineraries are offered ranging from 5 to 44 days on ships large and small. Call now or book online to receive exclusive rates and special offers on your next South America cruise.
Costa Diadema
Roundtrip Itajai
Mar 28 - Apr 11, 2026
Fr $563
SH Vega
Salvador to Rio de Janeiro
Oct 25, 2026
Fr $4,400
MSC Lirica
Roundtrip Itajai
Dec 13, 2026 - Mar 7, 2027
Fr $799
Crystal Serenity
Rio de Janeiro to Buenos Aires
Nov 4, 2027
Fr $3,634
Scenic Eclipse
Panama City/Panama to Valparaiso
Oct 26, 2026
Fr $7,581
Seven Seas Mariner
Rio de Janeiro to Buenos Aires
Jan 22, 2027
Fr $9,531
Azamara Quest
San Antonio/Chile to Fuerte Amador
Mar 2, 2026
Fr $3,216
Celebrity Equinox
Roundtrip Buenos Aires
Feb 28, 2026 - Feb 13, 2028
Fr $1,506
Carnival Firenze
Long Beach to San Antonio/Chile
Jan 4, 2027
Fr $1,337
Majestic Princess
San Antonio/Chile to Buenos Aires
Dec 22, 2026
Fr $1,875
Oosterdam
San Antonio/Chile to Buenos Aires
Dec 4, 2026
Fr $2,296
Seabourn Venture
Bridgetown to Rio de Janeiro
Oct 13, 2026 & Oct 9, 2027
Fr $6,247
World Traveller
Buenos Aires to Ushuaia
Nov 12, 2026
Fr $17,642
Queen Anne
Fort Lauderdale to Rio de Janeiro
Jan 22, 2027
Fr $3,079
Viking Jupiter
Buenos Aires to Valparaiso
Dec 2, 2026 - Feb 10, 2028
Fr $8,099
Queen Anne
Roundtrip Fort Lauderdale
Jan 22, 2027
Fr $10,866
National Geographic Explorer
Roundtrip Puerto Natales
Feb 17, 2026 - Feb 14, 2027
Fr $11,547
National Geographic Explorer
Roundtrip Puerto Natales
Feb 17, 2026 - Feb 29, 2028
Fr $11,547
National Geographic Explorer
Roundtrip Puerto Natales
Feb 17, 2026 - Feb 14, 2027
Fr $11,547
World Traveller
Roundtrip Ushuaia
Feb 25 & Mar 6, 2026
Fr $11,290
World Voyager
Roundtrip Ushuaia
Feb 27 & Mar 19, 2026
Fr $12,478
SH Minerva
Roundtrip Ushuaia
Nov 7 - Dec 27, 2026
Fr $11,200
Silver Cloud
Roundtrip Puerto Williams
Jan 8 & Feb 2, 2027
Fr $16,416
MS Fridtjof Nansen
Roundtrip Ushuaia
Feb 7 - Nov 29, 2026
Fr $10,661
MS Fridtjof Nansen
Roundtrip Ushuaia
Feb 7 - Mar 9, 2026
Fr $10,661
Seabourn Venture
Buenos Aires to Ushuaia
Feb 28, 2026
Fr $12,140
Viking Polaris
Buenos Aires to Ushuaia
Feb 10, 2026 - Feb 26, 2027
Fr $15,995
Scenic Eclipse
Roundtrip Buenos Aires
Feb 13, 2026 - Feb 17, 2027
Fr $18,937
Celebrity Equinox
Roundtrip Buenos Aires
Jan 2 - 30, 2027
Fr $3,486
Majestic Princess
Roundtrip Buenos Aires
Jan 6 & 23, 2027
Fr $2,950
SH Vega
Fortaleza to Belem
Apr 17, 2027
Fr $6,575
Explora I
San Juan to Manaus
Feb 5, 2027
Fr $8,930
Explora I
Manaus to San Juan
Feb 17, 2027
Fr $9,405
Silver Nova
Bridgetown to Rio de Janeiro
Jan 18, 2027
Fr $20,352
Insignia
Rio de Janeiro to Miami
Mar 19, 2027
Fr $5,153
Marina
Rio de Janeiro to Miami
Mar 17, 2026
Fr $6,717
Viking Sea
Roundtrip San Juan
Dec 15, 2026
Fr $11,499
Seven Seas Mariner
Roundtrip Miami
Nov 9, 2026
Fr $13,636
Crystal Serenity
Roundtrip Fort Lauderdale
Jan 18, 2028
Fr $11,010
Volendam
Roundtrip Fort Lauderdale
Nov 25, 2026
Fr $4,975
Volendam
New York City to Fort Lauderdale
Nov 22, 2026
Fr $4,996
All offers are based on select sailings and categories and are subject to availability at time of booking. All rates are per person based on double occupancy.
Dramatic Landscapes
The spectacular sights that await you on a cruise to South America include the thundering Iguazu Falls, the Straits of Magellan and Cape Horn's stunning glaciers and fjords. Visit the remote Falkland Islands and journey to Ushuaia, located at the End of the World. Some South American cruises can even take you to Antarctica for a true adventure of a lifetime.
Incredible Machu Picchu
Machu Picchu is one of the most beautiful and enigmatic historical sites in the world. Nested high in the Andes Mountains, far above the clouds, Machu Picchu is the ancient capital of the Inca civilization and is a remarkable sight to behold. It has been revered as a sacred and mystical place and is one of UNESCO's World Heritage Sites.
Incredible Wildlife
The wildlife of South America is as diverse as it is spectacular. It is one of the few places in the world where you can see penguin colonies, condors, whales, sea lions and elephant seals living in their natural habitat. A South America cruise is one of the best ways to see these magnificent creatures.
History and Culture
Take a South America cruise and explore its exciting cities and become immerse in their varied cultures. Visit the city of Rio De Janeiro and take in its Portuguese history. Learn to Tango in Buenos Aires and savor the cuisine in its wonderful restaurants. Enjoy the beautiful wine region near Santiago, Chile and get acquainted with the colonial city of Lima.